By Martin Frith, Christian Nørgaard Storm Pedersen

This booklet constitutes the refereed lawsuits of the sixteenth overseas Workshop on Algorithms in Bioinformatics, WABI 2016, held in Aarhus, Denmark. The 25 complete papers including 2 invited talks offered have been conscientiously reviewed and chosen from fifty four submissions.

The chosen papers conceal quite a lot of themes from networks, tophylogenetic reports, series and genome research, comparative genomics, and mass spectrometry information research.

**Read Online or Download Algorithms in Bioinformatics: 16th International Workshop, WABI 2016, Aarhus, Denmark, August 22-24, 2016. Proceedings PDF**

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**Extra info for Algorithms in Bioinformatics: 16th International Workshop, WABI 2016, Aarhus, Denmark, August 22-24, 2016. Proceedings**

**Example text**

2. 3. 4. q is a subsequence of some interval of length d in Q, tij is a subsequence of some interval in Iij for each 1 ≤ j ≤ k, i1 = i2 = · · · = ik , and q ≡ tij for each 1 ≤ j ≤ k. We say that a block {q, ti1 , . . , tik } is maximal in (Q, I, d) if there is no other block {q , tj1 , . . , tj } in this instance where q is a subsequence of q and {i1 , . . , ik } ⊆ {j1 , . . , j }. Definition 2 (Reference Anchored Gene Blocks Problem (RAGB)). The Reference Anchored Gene Blocks problem is the problem of computing all maximal blocks in a given problem instance (Q, I, d).

Moreover, note that in the same amount of time we can actually count the number of diﬀerent colorful bicliques (A , B ) corresponding to some A ⊆ A[i, i + d]. This is done by a simple combinatorial computation that considers all possibilities of picking a single vertex out of each color in BA . Lemma 6. Colorful Block Bipartite Biclique can be solved in O(2d nm) time. 4 Methods We implemented the algorithm for the RAGB2 problem in a program called RAGB Monitor (Reference-Anchored Gene Blocks Monitor).

Note however that the main issue with the Bipartite Biclique problem is that we assume that the number of edges in a solution biclique will be rather small, and can thus be taken as a parameter. This is not the case for the Block Bipartite Biclique problem. As we will see in the next section, this latter problem is ﬁxed-parameter tractable with respect to d, which for our purposes is much smaller than the number of edges in a solution biclique. The biological motivation for RAGB1 and RAGB2 naturally yields small bounds on d.